Be based on comfortable system – the interlining type biosensor of antibody and the interlining type biosensor that are based on comfortable system conjugate

 

Be Professor Man Bock Gu below interview a record.

 

Ask: You whether explain why be biosensor?

 

Answer: Biosensor can diagnose a disease or detect virus, and harmful to the mankind and environment material. Biosensor normally very small and convenient operation. A biosensor should have 3 big main package: Biology accepts put oneself in another’s position (biology element) , transducer (carry electricity or generate signal solely) with converter (can be read through color or other magnanimity take) . Ideal biosensor is OK and relaxed comfortable match any application.

 

Ask: You whether brief characterization the research domain that you try hard for it all the time?

 

Answer: We are developing the biosensor that is based on comfortable system, can choose didymous comfortable system especially. Comfortable system is to issue generation biology to accept put oneself in another’s position, by DNA or composition of RNA nucleic acid, replace the antibody that can be united in wedlock with particularity drone photograph. Generally speaking, use individual the biosensor of comfortable system is generated in signal or reappearance respect is not stable. This is the reason that great majority commercializes biosensor to use a pair to accept put oneself in another’s position (comfortable system or antibody) . Accordingly, we are devoting oneself to to develop a pair of comfortable system, can differ in two at the same time the drone with a dot same union, make sandwich structure (drone of comfortable system 1- – comfortable system 2) become a possibility. In fact, we have our comfortable system to develop a technology, can develop a pair of comfortable system successfully, we call this kind of method “Graphene-oxide SELEX (GO-SELEX) ” . Through using this kind of GO-SELEX, we can have indicated to include protein live thing content and virus differ a few kinds inside mark target development gives many pairs of comfortable put oneself in another’s position, and extraordinary success, enough proves the advantage of this technology.

 

 

Ask: Compare with other platform photograph, what are the main good point of the interlining type biosensor that is based on comfortable system and defect?

 

Answer: With what be based on comfortable system onefold biosensor photograph is compared, the advantage of the interlining type biosensor that is based on comfortable system is sensitivity and stability. Because be based on the interlining type sensor of comfortable system to use two kinds of different comfortable system, main comfortable system captures drone, the 2nd comfortable system and the drone that generate signal are united in wedlock, use Jinnami is particle, enzymatic wait for OK and independent enlarge to add the signal that is united in wedlock with drone. In addition, because signal is,arise independently from the 2nd comfortable system, signal is very accordingly stable and repeatability is good.

 

Ask: What is the potential application that you think this studies?

 

Answer: Apparent, these interlining type biosensor that are based on comfortable system can apply at transverse flow to determine, for example box of gravid diagnostic reagent. The interlining type biosensor that is based on comfortable system still can be used at diagnosing human body disease, detect the contaminant in epidemic virus or food and environment.

 

Ask: About this a series of research, in what be still put to challenge or difficult?

 

Answer: In very complex medium (be like blood or fecal) in development drone comfortable system remains a challenge. In addition, find be less than 1000 Dalton (Daltons) conjugate of young member comfortable system also has challenge sex very much.

 

 

Ask: What does this domain still have to be worth expectant progress?

 

Answer: A lot of research groups are using comfortable system to develop the biosensor of all sorts of types. Transverse measure stream determine (Lateral Flow Strip Assay, LFSA) have appeal especially with electrochemistry sensor, afore-mentioned platform are used easily and have convenience sex and portable sex.

 

Ask: Are you won to be on conference of biology project institute was ” of “ optimal paper made 2018 why impressions?

 

Answer: We are very glad to can obtain this special honour, I hope this award can let more reader pay close attention to paper and ” biology project ” periodical.